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40C self-heating compresses

For the eye relief of the ocular symptoms caused by the eyelids

The epidemiological statistics of blepharitis and dry eyes.

The international epidemiological statistics are not at all encouraging. The vulnerability of the eyes is evident and the need for the adoption of new health measures regarding eyelid & eyelashes hygiene seems imperative, as it is a practice that has the potential to lead to the improvement of the quality of vision and the quality of life of a large part of the population.
Blepharitis is defined as the common inflammation of the eyelids and eyelashes that is often accompanied by dry eyes and is seen in 37-47% of people visiting the ophthalmologist or the optometrist in the USA.
Dry eye occurs when the eyes for some reason (e.g. eyelid inflammation) do not produce enough or good quality tears that have the ability to stay the required amount of time on the ocular surface, for a stable and healthy tear film to exist. This can make your eyes feel uncomfortable, having a negative impact in your appearance and the quality of vision.
Up to 50% of the population suffers from some form of dry eyes, while 50% of dry eye patients also suffer from anterior blepharitis.
Blepharitis in many cases happens because of poor to non-existent eyelid/eyelashes hygiene and the chronic growth of bacteria and Demodex mites on the skin of the eyelids, resulting in chronic inflammation and ocular symptoms associated with: blepharitis, dry eyes, meibomianitis, chalazions, eyelid-conjunctivitis, trichiasis and madarosis. (ocular surface diseases)
Based on international clinical studies, it is apparent that the prevalence of Demodex mites plays an important pathological role together with bacteria:
65% of blepharitis is due to Demodex mites
84% over the age of 60 suffer from Demodex mites
90% of contact lens wearers has Demodex
91% of chalazions is attributed to Demodex mites
100% over the age of 70 suffer from Demodex
At the same time, it is clear that the ocular surface diseases mentioned above are related to chronic dermatological diseases such as atopic dermatitis, seborrheic dermatitis, rosacea and psoriasis:
40% of seborrheic dermatitis patients suffer from dry eyes
46% of blepharitis patients suffer from seborrheic dermatitis
51.4% of Rosacea patients suffer from ocular symptoms such as red eyes, itching, dry eyes, stye or chalazion
67% of psoriasis patients have ocular symptoms of blepharitis and dry eyes due to the chronic systemic inflammation of the disease
75% of rosacea patients have ocular involvement which is often under-diagnosed by dermatologists
84.2% of blepharitis patients have simultaneously at least one facial dermatosis such as facial demodicosis, seborrheic dermatitis, rosacea, eyelid dermatitis, ocular rosacea

What does eyelid and eyelashes hygiene include?

Due to the multifactorial pathologic nature of ocular surface diseases, eyelid/eyelashes treatment must be multifaceted and long-term for the successful management of the inflammation, having no symptoms a great appearance and an elevated quality of life. Eyelid hygiene includes decongestion, cleansing, massaging and spraying the eyelids & eyelashes, steps which will rejuvenate the eyes on many levels: 40C decongestive heating therapy of the eyelids with the pioneering self-heating disposable compresses is essential for the treatment of meibomian gland dysfunction (MGD), blepharitis, dry eyes and chalazion. (Ophthalmogen Eye10) Cleansing of the eyelids & eyelashes with the ophthalmic golden standard anti-inflammatory foam and wipes containing the right amount of tea tree oil is essential in controlling the bacterial load. (Naviblef) Massaging the eyelids with the unique anti-demodex & antibacterial Gel will contribute substantially in releasing the flow of lipids from the inflamed eyelids to the ocular surface, which will result in the rapid relief of blepharitis and dry eye symptoms. (Ophthalmogen Gel) Spraying the eyelids and eyelashes will significantly contribute in the healthy and vibrant condition of the eyelids & eyelashes in women who strain their eyes with frequent make up use, eyelash extensions and contact lenses. (Ophthalmogen Spray) The removal of the accumulated meibum from the eyelids, using the state of the art medical process of meibomian gland expression can significantly improve the overall effectiveness of the eyelids & eyelashes hygiene protocol. The meibomian glands produce a lipid rich secretion called meibum that is spread onto the tear film on the ocular surface with each blink. Expressing the valuable meibum from the blocked meibomian glands will accelerate treatment efficacy and patient satisfaction. The meibomian gland freeing procedure can only be administered by a skilled and experienced ophthalmologist, for the successful removal of ductal obstruction. The use of the Ophthalmogen Meibo-Evacuators is the most powerful natural treatment of strengthening the quality of the tear film an ophthalmologist can offer you, on top of the eyelid hygiene. Clinical trial findings include greater improvement in ocular symptom score, OSDI, TFBUT, and meibum quality and expressibility with manual expression through the application delicate and controlled pressure on the eyelids used as an adjunct to conventional treatment alone. Many clinicians prefer the use of Ophthalmogen Eye10 compresses & the Gel massage for at least 1-2 months prior to the in-office manual expression for the smooth secretion of the impacted meibum.

Which is the ideal blepharitis and dry eyes treatment?

You will be amazed how symptoms will resolve just with 40C heat, cleansing, massaging and spraying. Because of the multifactorial pathological nature of blepharitis and dry eyes, the ideal treatment should be multifaceted and long-term to be considered successful. First of all the most powerful therapeutic approach to these conditions involves the decongestion of the eyelids from the accumulated lipid oil, restoration of the smooth functioning of the lipid glands and control of the inflammation existing in the eyelids. These can be achieved by repeated 40C heating treatment combined with eyelid cleansing with Naviblef, eyelid massage with Ophthalmogen Gel and spraying with Ophthalmogen Spray. By restoring the function of the meibomian glands and releasing the blocked flow of lipids from the eyelids to the ocular surface, the symptoms of blepharitis and dry eyes will be drastically reduced and the improvement in the quality of life will be felt immediately. Throughout the course of treatment frequent instillation of lubricating eye drops should take place so that the eyes exogenously receive the hydration and protection they lack compared to the one healthy tears normally provide. It is logical that with the substantial improvement of the symptomatology, for the treatment to come to an end, but this is not recommended if there is a desire to maintain the good state of eye health that has been achieved. Due to the chronicity and complexity of the ocular surface diseases, a maintenance treatment is required in most cases for the long-term control of the inflammation, to avoid recurrence and above all to maintain a high quality of life.

The epidemiological statistics of Demodex and contact lens use.

It is well known that contact lenses and eye makeup burden eyelid &s eyelashes health especially in the absence of the necessary daily eyelid hygiene. Eye irritations and discomfort are not at all rare in this group of people.

The reason is that often in contact lens wearers there is an increased growth of Demodex parasites colonies on the eyelids and eyelashes according to clinical studies. Because of the effect of Demodex on normal eye flora or lid health, contact lenses may provide a more favorable environment for the multiplication of Demodex parasites..

It has been found that blepharitis can lead to increased deposits on contact lenses and consequently increased discomfort. At the same time, it has been found that contacts can provide a favorable environment for Demodex infestation which is associated with colonization of the eyelid margin by microorganisms such as Staphylococcus epidermidis, Propionibacterium acnes, Corynebacteria and Staphylococcus aureus. The same microorganisms have been found more commonly to grow easily in contact lens wearers. It is possible that contact lenses may provide a more favorable environment for bacterial growth and act as a carrier for microorganisms, which may lead to further Demodex infestation. 

International scientific studies demonstrate that:

90% of contact lens wearers have Demodex

50% of contact lens wearers develop dry eye symptoms

27.4% of contact lens users stop using their contacts usually due to intolerance symptoms from the very first year

Due to the high epidemiological statistics of blepharitis and dry eyes in both the general population and contact lens wearers, the need for daily eyelid/eyelashes hygiene is more imperative than ever to achieve a better quality of vision-comfort-appearance-quality of life and combat Contact Lens Drop Out.

What can be the cause of meibomian gland dysfunction?

The meibomian or lipid glands of the eyelids can get blocked and dysfunctional because of the inflammation of the eyelids that can be attributed to:
Chronic undiagnosed eyelid inflammation
Insufficient eyelid & eyelashes hygiene
Overgrowth of Demodex parasites and bacteria on the eyelids and eyelashes
Bacterial biofilm
Make up use (mascara, eye liner, eye shadows)
Contact lens use
Antiglaucoma eye drops

Dry eyes is synonymous to Meibomian gland dysfunction?

Meibomian gland dysfunction in the eyelids is a contributing factor to dry eyes that should be brought to the attention of clinicians, because otherwise they are treating dry eyes without treating the cause. Overcoming the blockage of the meibomian glands is an essential step in the treatment of dry eyes. The systemic use of 40C heat on the eyelids essentially contributes to the opening of the lipid/meibomian glands improving functionality and increasing the flow of lipids from the eyelids to the ocular surface resulting in the stabilization of the tear film and the slowing down of tear evaporation. Eyelid hygiene consisting of eyelid warming, cleansing, massaging and spraying, reduces the proliferation of bacteria and parasites that are believed to cause inflammation and increase the melting temperature of the meibum.

Ophthalmogen Eye10 provides:

Fast and long lasting blepharitis and dry eyes relief Relief from puffy eyelids and eye strain High levels of patient compliance, comfort and pleasure to the treatment Visual optimization because of the stabilization and refractive normalization of the tear film

Who is suitable to use the Ophthalmogen 40C self-heating compresses?

People diagnosed with blepharitis, dry eyes, chalazion and contact lens users are the first candidates for using the self-heating eye compresses. 40C self-heating compresses provide a very pleasurable and comforting feeling also to people using electronic devices for many hours and feel their eyes tired. Repetitive 40C thermal treatment of the eyelids has the potential to improve the tear film condition and ocular comfort regardless of the pathological state. The combination with the Ophthalmogen Gel eyelid massage can significantly improve pathological symptoms.

What contributes to the dysfunction of Meibomian glands of the eyelids?

Androgens are regulators of the expression of thousands of genes in the Meibomian glands Involving pathways of lipid dynamics. MGD is seen in people who are on anti-androgen agents, are using 13-cis-retinoid acid, topical antiglaucoma medications, use of contact lenses, live in low humidity environment and of course non-existent eyelid hygiene. Demodex and bacterial overgrowth on the eyelids and eyelashes is a defining factor linking blepharitis, dry eyes, meibomianitis and chalazion. Demodex mites on the skin of the eyelids can cause significant problems when they grow in large numbers (mainly due to poor hygiene) resulting in the well known demodicosis. The result can be inflammation of the eyelids, blockage of the meibomian glands, dry eyes, Weakening and shedding of the eyelashes. Rosacea and seborrheic dermatitis play an important role in the pathophysiology of meibomian gland dysfunction. (MGD)

Can skin health affect ocular health, what is the connection?

Rosacea is a common chronic inflammatory condition of the central face affecting the cheeks, nose, chin, forehead but can have ocular and systemic inflammatory associations. ¾ of rosacea patients have ocular involvement which is often underdiagnosed. In ocular rosacea, meibomian gland dysfunction (MGD) is a recognized manifestation which is also often found in association with seborrheic dermatitis according to James Mc Culley MD 1982 . Dry eyes which is the most common eye disorder is frequently accompanied by blepharitis which has an overall prevalence of nearly 40%, ranging from around 20% in 10-19 year old’s to 70% in those over 60 years of age. Blepharitis affects people of all ages, ethnicities, gender and in women the falling eyelashes can one of the symptoms of eyelid inflammation. According to clinical studies 56% of rosacea patients are considered to have mild to moderate dry eyes while 40.6% of rosacea patients seem to suffer from moderate to severe dry eyes. Dry eyes seems to occur frequently in rosacea and it is important for dermatologists and ophthalmologists to be aware of the frequency of dry eyes in rosacea.

What is Ophthalmogen Eye10?

They are the innovative self-heating eye compresses which provide the clinically studied 40C therapeutic temperature for the time needed to rejuvenate the eyes and treat the symptoms of blepharitis, dry eyes, chalazions and improve the quality of life. You are not satisfied with lubricating eye drops use? Why you should immediately include the 40C self-heating therapy in your life? Blepharitis and dry eyes can only be successfully managed if the treatment addresses the underlying causes. Using the 40C self-heating disposable compresses for a few months (depending on the intensity of the symptoms) is the first step towards a satisfying therapy. Recent ophthalmological scientific data from Asia rank the 40C heat treatment of the eyelids at the highest level in terms of long-term eye relief. The use of lubricating eye drops, monodoses and sprays (e.g the latest generation in ocular lubrication such as Visionlux Plus, Navitae Plus, Flora Vision Spray) is very widespread and extremely soothing but can only be complementary treatment in case of blepharitis and dry eyes with moderate to severe symptoms, if of course the goal is to achieve long-term relief.

Is the patient's ophthalmological history important?

The answer is, “Yes, it is very important.” Physicians can understand very clearly that the past matters. Health is heavily influenced by the past: heredity, past behaviors, past experiences, past diseases. All these data provide clues for a patients present health condition. Literally the past helps understand the present and develop strategies to solve current problems and advance the cause of medicine. When it comes to the eyes we have to think what has gone wrong till today and epidemiology of ocular surface diseases is soaring sky high? At some point in the past, the use of heat as an ophthalmic practice with warm compresses was very important in the treatment and calming of the eyes. At that era, life wasn’t running at the high pace of today’s living. As the pace of life accelerated, the use of hot compresses ceased to exist both due to the lack of time and the difficulty of providing the stable 40C therapeutic temperature for the 20’ period that is proven to be beneficial to the eyes. As a result of the accelerated daily life, can be the eyelids pathology with the appearance inflammation of the eyelids & eyelashes, dry eyes, meibomian gland dysfunction, chalazions, madarosis etc. Ophthalmogen 40C eyelid compresses have been designed according to modern daily life needs and current scientific findings. Systemic thermal application treatment of common ocular surface diseases will provide rapid and long-lasting relief, contributing to the reduction of the high epidemiological statistics.
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