Introduction
Chalazion, an inflammatory cyst that forms on the eyelid due to blockage of the meibomian glands, is more common in patients with Sjögren’s syndrome and other autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, thyroid disorders).
Severe dry eye, chronic inflammation, and immunosuppression make chalazion more frequent, more persistent, and more prone to recurrence.
Why Are Sjögren’s & Autoimmune Patients at Higher Risk?
- Severe Dry Eye
In Sjögren’s, autoimmune destruction of the lacrimal glands leads to tear film instability and meibomian gland obstruction.
- Meibomian gland dysfunction (MGD)
Up to 50% of patients with Sjögren’s have MGD → higher risk of chalazion.
- Immunosuppression
Medications such as corticosteroids, immunosuppressants, and biologics reduce defense and delay healing.
- Associated Skin Disorders
Autoimmune diseases such as lupus or thyroid disorders can cause skin lesions that also affect the eyelids.
Statistics
- 80–90% of patients with Sjögren’s develop severe dry eye.
- 25–30% develop recurrent chalazia.
- Immunosuppressed patients have twice the risk of infection.
Symptoms
- Firm, persistent eyelid nodules.
- Frequent recurrences.
- Dry eye, burning, blurred vision.
- More discomfort and delayed healing.
Complications
- Recurrent chalazia and chronic blepharitis.
- Secondary infections due to reduced immunity.
- Eyelash loss (madarosis) and misdirected lashes (trichiasis).
- Reduced quality of life.
Prevention – The Dermophthalmology Approach
Daily eyelid hygiene is critical for patients with Sjögren's and autoimmune diseases.
OphthalmogenEye10 – Single-Use Heat Compresses
- Sterile and safe for immunosuppressed patients.
- Provides stable heat at 40°C for 20 minutes.
- Softens and melts thickened secretions → gland drainage.
- Improves blood flow.
- Ideal for daily use at home.
OphthalmogenGel Massage, Hydration & Demodex regulation
- Applied after Eye10 with gentle massage.
- Hydrates, reduces inflammation.
- Controls Demodex, often increased in autoimmune patients.
- Protects eyelashes from loss and dystrophy.
Ophthalmogen Spray – All-Day Hydration & Antimicrobial Action
- Disinfects and hydrates eyelids and lashes.
- Reduces infection risk.
- Can be applied multiple times a day, even over makeup.
Additional Support
Artificial Tears
- Visionlux Plus DUO
- Hylo-Comod
- Systane
- Thealoz Duo
- Navi Infla
- Refresh
- Navitae Plus (hyaluronic acid + vitamins A & E, for extra hydration & antioxidant protection)
Συμπληρώματα Ωμέγα-3
- Allvita Eyes
- MacuShield, Macusave
- Solgar Omega-3
- Minami Omega-3
- Lamberts Omega-3
Immune System Support
- Vitamin C (1000mg με Zinc)
- Vitamin D3
- Zinc & Selenium
- Immunix OTOSAN (popular in Greece for chronic patients).
Medical Support
- Tobradex or Dexamytrex in inflammatory chalazions.
- Topical or oral antibiotics in infections.
- Close monitoring by ophthalmologists, especially in patients with severe immunosuppression.
Conclusion
Chalazion is particularly common in patients with Sjögren’s syndrome and other autoimmune diseases due to dry eye, MGD, immunosuppression, and chronic inflammation.
The Dermophthalmology protocol with Ophthalmogen (Eye10, Gel, Spray, Naviblef) combined with artificial tears (Visionlux Plus DUO), Omega-3 supplements (Solgar, Minami, Lamberts), and immune system support (Vitamin C, D3, Zinc, Selenium, Immunix OTOSAN) offers the most comprehensive and safe solution.
For autoimmune patients, proper daily eyelid care and immune support are not luxuries – they are essential for vision and quality of life.
Introducing Dermophthalmology – a modern field that comprehensively examines both eyes and skin. Find out more at www.dermophthalmology.com.
