
Introduction
Chalazion is a chronic inflammatory cyst of the eyelids caused by obstruction of the meibomian glands.
While usually considered a minor condition, in patients with psoriasis and dermatomyositis, chalazia occur more frequently, tend to persist, and are often recurrent.
Skin inflammation, autoimmune mechanisms, and immunosuppressive therapy explain this strong association.
Why Skin Autoimmune Diseases Increase the Risk
- Psoriasis
- Chronic skin inflammation also affects the eyelid skin.
- Often coexists with seborrheic dermatitis → blepharitis → MGD.
- Systemic treatments (methotrexate, biologics) lower local immunity.
- Dermatomyositis
- Causes periocular skin changes (redness, swelling, heliotrope rash).
- Chronic inflammation worsens meibomian gland function → chalazion.
- Frequent corticosteroid and immunosuppressive use → delayed healing.
- Common Pathway: Inflammation & Immunosuppression
Both conditions create an environment that favors chalazion: dry eye, inflammation, microbial overgrowth, and gland obstruction.

Statistics
- 20–30% of psoriasis patients develop blepharitis.
- 15% of psoriasis patients develop chalazion at some point.
- In dermatomyositis, periocular lesions are observed in up to 40% of cases.


Symptoms
- Persistent chalazia that do not resolve easily.
- Frequent recurrences.
- Redness, swelling, eyelid heaviness.
- Dry eye and burning sensation.
Complications
- Multiple chalazia.
- Chronic blepharitis.
- Secondary infections.
- Cosmetic & functional issues.
The Dermophthalmology Solution


Supportive Care
Artificial Tears
- Visionlux Plus DUO, Hylo-Comod, Systane, Thealoz Duo, Navitae Plus.
Eye Supplements and Omega-3
- Allvita Eyes, Solgar, Minami ,Ocuvite, Nutrof, Lamberts, MacuShield, MacuSave.
Vitamins & Immune Support
- Vitamin C, D3, Zinc, Selenium, Immunix OTOSAN.
OphthalmogenEye10 – Self-heating Compresses
- 40°C heat for 20 minutes.
- Softens meibum and unclogs the glands.
- Helps the eyes produce healthier tears – improving both quality and quantity, resulting in clearer and more comfortable vision
- Relieves dry eye frequently associated with psoriasis & dermatomyositis.
OphthalmogenGel – Massage & Anti-Demodex Action
- Gentle massage after Eye10.
- Controls inflammation, hydrates, reduces Demodex load.
- Enhances eyelid microcirculation and promotes healthier Meibomian Gland function, resulting in more refreshed, hydrated eyes with clear vision.
Ophthalmogen Spray – Ενυδάτωση & Αντιμικροβιακή Προστασία
- Hydrates and disinfects eyelids and lashes.
- Safe for multiple daily applications, even over makeup.
- Provides better nourishment of the eyelashes and optimizes their curvature, enhancing their functionality. This helps reduce the intensity of dry eye, red eyes, and blurred vision
Naviblef
- Daily cleansing solution to remove bacteria and excess oils.
- Creates the ideal healthy environment where parasites and bacteria cannot multiply, thereby improving the overall feeling and comfort of the eyes.
Προτεινόμενο Πρωτόκολλο Χρήσης
- Morning: Naviblef + Ophthalmogen Spray + artificial tears.
- Noon/Afternoon: Eye10 (20’) → Ophthalmogen Gel with gentle massage.
- Throughout the day: Ophthalmogen Spray + artificial tears as needed.
- Supplements: Allvita Eyes and Omega-3 and vitamins.


Conclusion
Chalazion in patients with psoriasis and dermatomyositis is more frequent, more inflammatory, and more resistant due to the nature of these diseases and immunosuppressive treatment.
The Dermophthalmology approach with Ophthalmogen (Eye10, Gel, Spray, Naviblef), combined with artificial tears, Omega-3, and vitamins, provides the most complete and safe preventive and therapeutic regimen.
For patients with skin autoimmune diseases, daily eyelid care is not a luxury – it is a necessity for vision and quality of life.
A new approach to eye and skin health: Dermophthalmology. Discover more at www.dermophthalmology.com.